How the regulator is regulated: Insight into immune-related protein holds therapeutic value

In immune-related disorders, therapy often involves identifying the molecules responsible for immune dysregulation and targeting them using drugs. This type of immune therapy is also used for cancer treatment, owing to the important role that immune cells play in cancer progression. One such type of a potential therapeutic target is an immune checkpoint protein called […]

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Stepping-down asthma medication may reduce costs without worsening health out

International guidelines for asthma treatment recommend clinicians find the minimum effective dose that can control symptoms, yet asthma patients are increasingly prescribed high doses of medication. A study published in PLOS Medicine by Dr. Chloe Bloom at Imperial College London, United Kingdom and colleagues found that stepping-down medication doses did not increase asthma exacerbations and […]

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Global warming boosts heat-related cardiovascular hospitalizations, study finds

The impact of high temperatures on hospitalizations due to cardiovascular diseases has increased over the past two decades in Queensland, Australia, according to a new study published this week in PLOS Medicine by Shanshan Li and Yuming Guo of Monash University, Australia, and colleagues. Extreme temperatures—both cold and hot—are known risk factors for cardiovascular morbidity […]

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New study shows advantages of ellipsys system in creating reliable dialysis access

A new study shows significant benefits of the Ellipsys Vascular Access System in easily and safely creating durable vascular access for end-stage renal disease (ESRD) patients who require hemodialysis. It also offers a standardized process for using the minimally invasive technology that other physicians can follow to reproduce the results, which “will make it easier […]

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Assessing symptoms, blood, stool markers best for identifying pediatric IBD

For pediatric patients with nonbloody diarrhea, evaluating symptoms plus blood and stool markers is the optimal test strategy for predicting inflammatory bowel disease (IBD), according to a study published online July 21 in Pediatrics. Els Van de Vijver, M.D., from University Hospital Antwerp in Edegem, Belgium, and colleagues conducted a prospective cohort study involving 193 […]

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